Research portfolio

From current trials to foundational studies

Every study now has a structured page connecting its objectives, team, timeline, partners, publications and findings.
CurrentCompletedLegacy / regional
Current Phase I clinical trialTherapeutic feeding

F50 Trial

Evaluating the safety and tolerability of lower-calorie therapeutic milk during early stabilisation of critically ill children with severe malnutrition.

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Acute illness and recovery

CHAIN Network / CHAIN Cohort

A multinational collaboration studying why acutely ill or undernourished young children remain at risk during hospitalisation and for months after discharge.

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Systems biology

CHAIN Nested Case-Cohort / Multi-Omics

Integrated biological research investigating mechanisms associated with mortality among acutely ill children.

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Completed multicentre randomized trialClinical trial

PB-SAM: Pancreatic Enzymes and Bile Acids Trial

Testing whether pancreatic enzymes and bile-acid treatment improve outcomes in hospitalised children with severe acute malnutrition.

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Completed with published findingsMortality research

MITS in Malawi

Minimally invasive tissue sampling improved cause-of-death attribution among children with acute illness and/or severe malnutrition.

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Completed CHAIN sub-studyDermatology and malnutrition

SkinCHAINges

Improving recognition and classification of skin manifestations associated with childhood malnutrition.

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Completed caregiver-focused interventionChild development and caregiving

Kusamala Program

Using the hospital stay to strengthen caregiving for children admitted with severe acute malnutrition.

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Completed nutrition interventionComplementary feeding

Mazira Project

Investigating whether one egg per day improves growth, development and nutritional biomarkers.

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Large therapeutic-food trialNutrition and neurodevelopment

High-Oleic RUTF Trial

Comparing therapeutic-food formulations for severe acute malnutrition and subsequent neurodevelopment.

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Regional longitudinal cohort researchLong-term outcomes

IAEA RAF6052

Examining body composition, cardiometabolic risk and physical activity after treatment for acute malnutrition.

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Programme evaluation researchMicronutrients

IAEA MLW6007

Evaluating multiple micronutrient powder delivered with infant and young-child feeding education.

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CHAIN follow-up pathway

Research extends beyond the hospital door to understand recovery and risk after discharge.

  1. Admission
  2. Discharge
  3. Day 45
  4. Day 90
  5. Day 180
info

Research history note: COSMIC, ATOMIC and other related studies will be added when investigator-approved summaries are available.

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